Campeonato Uruguayo – Apertura 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Plaza Colonia | 36 | 15 | 11 | 3 | 1 | 20 | 7 | 13 |
| 2 |  Nacional | 29 | 15 | 9 | 2 | 4 | 23 | 14 | 9 |
| 3 |  Peñarol | 28 | 15 | 7 | 7 | 1 | 22 | 10 | 12 |
| 4 |  Liverpool | 27 | 15 | 8 | 3 | 4 | 38 | 20 | 18 |
| 5 |  River Plate | 26 | 15 | 7 | 5 | 3 | 27 | 20 | 7 |
| 6 |  Montevideo City Torque | 25 | 15 | 8 | 1 | 6 | 26 | 19 | 7 |
| 7 |  Fénix | 21 | 15 | 6 | 3 | 6 | 20 | 22 | -2 |
| 8 |  Cerro Largo | 20 | 15 | 6 | 2 | 7 | 20 | 22 | -2 |
| 9 |  Cerrito | 19 | 15 | 5 | 4 | 6 | 14 | 15 | -1 |
| 10 |  Sud América | 18 | 15 | 5 | 3 | 7 | 15 | 22 | -7 |
| 11 |  Wanderers | 17 | 15 | 5 | 2 | 8 | 12 | 16 | -4 |
| 12 |  Rentistas | 16 | 15 | 4 | 4 | 7 | 12 | 21 | -9 |
| 13 |  Boston River | 14 | 15 | 3 | 5 | 7 | 14 | 19 | -5 |
| 14 |  Deportivo Maldonado | 14 | 15 | 3 | 5 | 7 | 11 | 22 | -11 |
| 15 |  Progreso | 11 | 15 | 2 | 5 | 8 | 13 | 26 | -13 |
| 16 |  Villa Española | 9 | 15 | 1 | 6 | 8 | 14 | 26 | -12 |
Campeonato Uruguayo – Clausura 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Wanderers | 9 | 3 | 3 | 0 | 0 | 8 | 3 | 5 |
| 2 | Peñarol | 7 | 3 | 2 | 1 | 0 | 7 | 3 | 4 |
| 3 | Liverpool | 6 | 3 | 2 | 0 | 1 | 4 | 4 | 0 |
| 4 | Cerro Largo | 5 | 3 | 1 | 2 | 0 | 5 | 2 | 3 |
| 5 | Fénix | 5 | 3 | 1 | 2 | 0 | 4 | 2 | 2 |
| 6 | Montevideo City Torque | 5 | 3 | 1 | 2 | 0 | 5 | 4 | 1 |
| 7 | Plaza Colonia | 4 | 3 | 1 | 1 | 1 | 7 | 4 | 3 |
| 8 | Nacional | 4 | 3 | 1 | 1 | 1 | 3 | 2 | 1 |
| 9 | Cerrito | 4 | 3 | 1 | 1 | 1 | 2 | 2 | 0 |
| 10 | Progreso | 4 | 3 | 1 | 1 | 1 | 2 | 2 | 0 |
| 11 | Deportivo Maldonado | 3 | 3 | 1 | 0 | 2 | 3 | 5 | -2 |
| 12 | River Plate | 3 | 3 | 1 | 0 | 2 | 3 | 5 | -2 |
| 13 | Sud América | 3 | 3 | 1 | 0 | 2 | 3 | 5 | -2 |
| 14 | Boston River | 3 | 3 | 1 | 0 | 2 | 5 | 9 | -4 |
| 15 | Villa Española | 1 | 3 | 0 | 1 | 2 | 2 | 7 | -5 |
| 16 | Rentistas | 0 | 3 | 0 | 0 | 3 | 3 | 7 | -4 |
Campeonato Uruguayo – Anual 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Plaza Colonia | 40 | 18 | 12 | 4 | 2 | 27 | 11 | 16 |
| 2 | Peñarol | 35 | 18 | 9 | 8 | 1 | 29 | 13 | 16 |
| 3 | Liverpool | 33 | 18 | 10 | 3 | 5 | 42 | 24 | 18 |
| 4 | Nacional | 33 | 18 | 10 | 3 | 5 | 26 | 16 | 10 |
| 5 | Montevideo City Torque | 30 | 18 | 9 | 3 | 6 | 31 | 23 | 8 |
| 6 | River Plate | 29 | 18 | 8 | 5 | 5 | 30 | 25 | 5 |
| 7 | Wanderers | 26 | 18 | 8 | 2 | 8 | 20 | 19 | 1 |
| 8 | Fénix | 26 | 18 | 7 | 5 | 6 | 24 | 24 | 0 |
| 9 | Cerro Largo | 25 | 18 | 7 | 4 | 7 | 25 | 24 | 1 |
| 10 | Cerrito | 23 | 18 | 6 | 5 | 7 | 16 | 17 | -1 |
| 11 | Sud América | 21 | 18 | 6 | 3 | 9 | 18 | 27 | -9 |
| 12 | Boston River | 17 | 18 | 4 | 5 | 9 | 19 | 28 | -9 |
| 13 | Deportivo Maldonado | 17 | 18 | 4 | 5 | 9 | 14 | 27 | -13 |
| 14 | Rentistas | 16 | 18 | 4 | 4 | 10 | 15 | 28 | -13 |
| 15 | Progreso | 15 | 18 | 3 | 6 | 9 | 15 | 28 | -13 |
| 16 | Villa Española | 10 | 18 | 1 | 7 | 10 | 16 | 33 | -17 |
Campeonato Uruguayo – Descenso 2021
| Pos | Club | Pts | Promedio | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Nacional | 102 | 1.855 | 55 | 29 | 15 | 11 | 83 | 54 | 29 |
| 2 | Peñarol | 100 | 1.818 | 55 | 27 | 19 | 9 | 83 | 49 | 34 |
| 3 | Liverpool | 98 | 1.782 | 55 | 28 | 14 | 13 | 112 | 74 | 38 |
| 4 | Montevideo City Torque | 91 | 1.655 | 55 | 26 | 13 | 16 | 95 | 63 | 32 |
| 5 | Plaza Colonia | 86 | 1.564 | 55 | 23 | 17 | 15 | 77 | 56 | 21 |
| 6 | River Plate | 78 | 1.418 | 55 | 21 | 15 | 19 | 80 | 74 | 6 |
| 7 | Wanderers | 78 | 1.418 | 55 | 21 | 15 | 19 | 71 | 74 | -3 |
| 8 | Cerro Largo | 75 | 1.364 | 55 | 19 | 18 | 18 | 67 | 63 | 4 |
| 9 | Fénix | 75 | 1.364 | 55 | 18 | 21 | 16 | 75 | 71 | 4 |
| 10 | Cerrito | 23 | 1.278 | 18 | 6 | 5 | 7 | 16 | 17 | -1 |
| 11 | Sud América | 21 | 1.167 | 18 | 6 | 3 | 9 | 18 | 27 | -9 |
| 12 | Deportivo Maldonado | 63 | 1.145 | 55 | 15 | 18 | 22 | 61 | 89 | -28 |
| 13 | Rentistas | 63 | 1.145 | 55 | 15 | 18 | 22 | 60 | 76 | -16 |
| 14 | Boston River | 57 | 1.036 | 55 | 14 | 15 | 26 | 62 | 85 | -23 |
| 15 | Progreso | 53 | 0.964 | 55 | 12 | 17 | 26 | 60 | 80 | -20 |
| 16 | Villa Española | 10 | 0.556 | 18 | 1 | 7 | 10 | 16 | 33 | -17 |