Campeonato Uruguayo – Apertura 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Plaza Colonia | 36 | 15 | 11 | 3 | 1 | 20 | 7 | 13 |
| 2 |  Nacional | 29 | 15 | 9 | 2 | 4 | 23 | 14 | 9 |
| 3 |  Peñarol | 28 | 15 | 7 | 7 | 1 | 22 | 10 | 12 |
| 4 |  Liverpool | 27 | 15 | 8 | 3 | 4 | 38 | 20 | 18 |
| 5 |  River Plate | 26 | 15 | 7 | 5 | 3 | 27 | 20 | 7 |
| 6 |  Montevideo City Torque | 25 | 15 | 8 | 1 | 6 | 26 | 19 | 7 |
| 7 |  Fénix | 21 | 15 | 6 | 3 | 6 | 20 | 22 | -2 |
| 8 |  Cerro Largo | 20 | 15 | 6 | 2 | 7 | 20 | 22 | -2 |
| 9 |  Cerrito | 19 | 15 | 5 | 4 | 6 | 14 | 15 | -1 |
| 10 |  Sud América | 18 | 15 | 5 | 3 | 7 | 15 | 22 | -7 |
| 11 |  Wanderers | 17 | 15 | 5 | 2 | 8 | 12 | 16 | -4 |
| 12 |  Rentistas | 16 | 15 | 4 | 4 | 7 | 12 | 21 | -9 |
| 13 |  Boston River | 14 | 15 | 3 | 5 | 7 | 14 | 19 | -5 |
| 14 |  Deportivo Maldonado | 14 | 15 | 3 | 5 | 7 | 11 | 22 | -11 |
| 15 |  Progreso | 11 | 15 | 2 | 5 | 8 | 13 | 26 | -13 |
| 16 |  Villa Española | 9 | 15 | 1 | 6 | 8 | 14 | 26 | -12 |
Campeonato Uruguayo – Clausura 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Wanderers | 6 | 2 | 2 | 0 | 0 | 6 | 2 | 4 |
| 2 | Liverpool | 6 | 2 | 2 | 0 | 0 | 4 | 1 | 3 |
| 3 | Fénix | 4 | 2 | 1 | 1 | 0 | 3 | 1 | 2 |
| 4 | Montevideo City Torque | 4 | 2 | 1 | 1 | 0 | 4 | 3 | 1 |
| 5 | Peñarol | 4 | 2 | 1 | 1 | 0 | 2 | 1 | 1 |
| 6 | Progreso | 4 | 2 | 1 | 1 | 0 | 2 | 1 | 1 |
| 7 | Sud América | 3 | 2 | 1 | 0 | 1 | 3 | 3 | 0 |
| 8 | Boston River | 3 | 2 | 1 | 0 | 1 | 3 | 4 | -1 |
| 9 | River Plate | 3 | 2 | 1 | 0 | 1 | 2 | 3 | -1 |
| 10 | Cerro Largo | 2 | 2 | 0 | 2 | 0 | 2 | 2 | 0 |
| 11 | Plaza Colonia | 1 | 2 | 0 | 1 | 1 | 3 | 4 | -1 |
| 12 | Villa Española | 1 | 2 | 0 | 1 | 1 | 2 | 3 | -1 |
| 13 | Cerrito | 1 | 2 | 0 | 1 | 1 | 1 | 2 | -1 |
| 14 | Nacional | 1 | 2 | 0 | 1 | 1 | 1 | 2 | -1 |
| 15 | Rentistas | 0 | 2 | 0 | 0 | 2 | 2 | 5 | -3 |
| 16 | Deportivo Maldonado | 0 | 2 | 0 | 0 | 2 | 1 | 4 | -3 |
Campeonato Uruguayo – Anual 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Plaza Colonia | 37 | 17 | 11 | 4 | 2 | 23 | 11 | 12 |
| 2 | Liverpool | 33 | 17 | 10 | 3 | 4 | 42 | 21 | 21 |
| 3 | Peñarol | 32 | 17 | 8 | 8 | 1 | 24 | 11 | 13 |
| 4 | Nacional | 30 | 17 | 9 | 3 | 5 | 24 | 16 | 8 |
| 5 | Montevideo City Torque | 29 | 17 | 9 | 2 | 6 | 30 | 22 | 8 |
| 6 | River Plate | 29 | 17 | 8 | 5 | 4 | 29 | 23 | 6 |
| 7 | Fénix | 25 | 17 | 7 | 4 | 6 | 23 | 23 | 0 |
| 8 | Wanderers | 23 | 17 | 7 | 2 | 8 | 18 | 18 | 0 |
| 9 | Cerro Largo | 22 | 17 | 6 | 4 | 7 | 22 | 24 | -2 |
| 10 | Sud América | 21 | 17 | 6 | 3 | 8 | 18 | 25 | -7 |
| 11 | Cerrito | 20 | 17 | 5 | 5 | 7 | 15 | 17 | -2 |
| 12 | Boston River | 17 | 17 | 4 | 5 | 8 | 17 | 23 | -6 |
| 13 | Rentistas | 16 | 17 | 4 | 4 | 9 | 14 | 26 | -12 |
| 14 | Progreso | 15 | 17 | 3 | 6 | 8 | 15 | 27 | -12 |
| 15 | Deportivo Maldonado | 14 | 17 | 3 | 5 | 9 | 12 | 26 | -14 |
| 16 | Villa Española | 10 | 17 | 1 | 7 | 9 | 16 | 29 | -13 |
Campeonato Uruguayo – Descenso 2021
| Pos | Club | Pts | Promedio | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Nacional | 99 | 1.833 | 54 | 28 | 15 | 11 | 81 | 54 | 27 |
| 2 | Liverpool | 98 | 1.815 | 54 | 28 | 14 | 12 | 112 | 71 | 41 |
| 3 | Peñarol | 97 | 1.796 | 54 | 26 | 19 | 9 | 78 | 47 | 31 |
| 4 | Montevideo City Torque | 90 | 1.667 | 54 | 26 | 12 | 16 | 94 | 62 | 32 |
| 5 | Plaza Colonia | 83 | 1.537 | 54 | 22 | 17 | 15 | 73 | 56 | 17 |
| 6 | River Plate | 78 | 1.444 | 54 | 21 | 15 | 18 | 79 | 72 | 7 |
| 7 | Wanderers | 75 | 1.389 | 54 | 20 | 15 | 19 | 69 | 73 | -4 |
| 8 | Fénix | 74 | 1.370 | 54 | 18 | 20 | 16 | 74 | 70 | 4 |
| 9 | Cerro Largo | 72 | 1.333 | 54 | 18 | 18 | 18 | 64 | 63 | 1 |
| 10 | Sud América | 21 | 1.235 | 17 | 6 | 3 | 8 | 18 | 25 | -7 |
| 11 | Cerrito | 20 | 1.176 | 17 | 5 | 5 | 7 | 15 | 17 | -2 |
| 12 | Rentistas | 63 | 1.167 | 54 | 15 | 18 | 21 | 59 | 74 | -15 |
| 13 | Deportivo Maldonado | 60 | 1.111 | 54 | 14 | 18 | 22 | 59 | 88 | -29 |
| 14 | Boston River | 57 | 1.056 | 54 | 14 | 15 | 25 | 60 | 80 | -20 |
| 15 | Progreso | 53 | 0.981 | 54 | 12 | 17 | 25 | 60 | 79 | -19 |
| 16 | Villa Española | 10 | 0.588 | 17 | 1 | 7 | 9 | 16 | 29 | -13 |