Campeonato Uruguayo – Apertura 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 |  Plaza Colonia | 36 | 15 | 11 | 3 | 1 | 20 | 7 | 13 |
| 2 |  Nacional | 29 | 15 | 9 | 2 | 4 | 23 | 14 | 9 |
| 3 |  Peñarol | 28 | 15 | 7 | 7 | 1 | 22 | 10 | 12 |
| 4 |  Liverpool | 27 | 15 | 8 | 3 | 4 | 38 | 20 | 18 |
| 5 |  River Plate | 26 | 15 | 7 | 5 | 3 | 27 | 20 | 7 |
| 6 |  Montevideo City Torque | 25 | 15 | 8 | 1 | 6 | 26 | 19 | 7 |
| 7 |  Fénix | 21 | 15 | 6 | 3 | 6 | 20 | 22 | -2 |
| 8 |  Cerro Largo | 20 | 15 | 6 | 2 | 7 | 20 | 22 | -2 |
| 9 |  Cerrito | 19 | 15 | 5 | 4 | 6 | 14 | 15 | -1 |
| 10 |  Sud América | 18 | 15 | 5 | 3 | 7 | 15 | 22 | -7 |
| 11 |  Wanderers | 17 | 15 | 5 | 2 | 8 | 12 | 16 | -4 |
| 12 |  Rentistas | 16 | 15 | 4 | 4 | 7 | 12 | 21 | -9 |
| 13 |  Boston River | 14 | 15 | 3 | 5 | 7 | 14 | 19 | -5 |
| 14 |  Deportivo Maldonado | 14 | 15 | 3 | 5 | 7 | 11 | 22 | -11 |
| 15 |  Progreso | 11 | 15 | 2 | 5 | 8 | 13 | 26 | -13 |
| 16 |  Villa Española | 9 | 15 | 1 | 6 | 8 | 14 | 26 | -12 |
Campeonato Uruguayo – Clausura 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Peñarol | 32 | 15 | 9 | 5 | 1 | 27 | 11 | 16 |
| 2 | Nacional | 30 | 15 | 9 | 3 | 3 | 23 | 15 | 8 |
| 3 | Cerro Largo | 28 | 15 | 7 | 7 | 1 | 24 | 11 | 13 |
| 4 | Wanderers | 27 | 15 | 8 | 3 | 4 | 23 | 18 | 5 |
| 5 | Montevideo City Torque | 25 | 15 | 7 | 4 | 4 | 26 | 19 | 7 |
| 6 | Progreso | 25 | 15 | 7 | 4 | 4 | 12 | 7 | 5 |
| 7 | Boston River | 22 | 15 | 6 | 4 | 5 | 24 | 25 | -1 |
| 8 | Cerrito | 21 | 15 | 6 | 3 | 6 | 20 | 22 | -2 |
| 9 | Plaza Colonia | 20 | 15 | 5 | 5 | 5 | 20 | 18 | 2 |
| 10 | Fénix | 19 | 15 | 4 | 7 | 4 | 18 | 18 | 0 |
| 11 | Deportivo Maldonado | 17 | 15 | 5 | 2 | 8 | 13 | 18 | -5 |
| 12 | River Plate | 16 | 15 | 4 | 4 | 7 | 18 | 22 | -4 |
| 13 | Liverpool | 15 | 15 | 4 | 3 | 8 | 15 | 19 | -4 |
| 14 | Rentistas | 14 | 15 | 4 | 2 | 9 | 18 | 24 | -6 |
| 15 | Sud América | 13 | 15 | 3 | 4 | 8 | 14 | 26 | -12 |
| 16 | Villa Española | 5 | 15 | 1 | 2 | 12 | 12 | 34 | -22 |
Campeonato Uruguayo – Anual 2021
| Pos | Club | Pts | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Peñarol | 60 | 30 | 16 | 12 | 2 | 49 | 21 | 28 |
| 2 | Nacional | 59 | 30 | 18 | 5 | 7 | 46 | 29 | 17 |
| 3 | Plaza Colonia | 56 | 30 | 16 | 8 | 6 | 40 | 25 | 15 |
| 4 | Montevideo City Torque | 50 | 30 | 15 | 5 | 10 | 52 | 38 | 14 |
| 5 | Cerro Largo | 48 | 30 | 13 | 9 | 8 | 44 | 33 | 11 |
| 6 | Wanderers | 44 | 30 | 13 | 5 | 12 | 35 | 34 | 1 |
| 7 | Liverpool | 42 | 30 | 12 | 6 | 12 | 53 | 39 | 14 |
| 8 | River Plate | 42 | 30 | 11 | 9 | 10 | 45 | 42 | 3 |
| 9 | Fénix | 40 | 30 | 10 | 10 | 10 | 38 | 40 | -2 |
| 10 | Cerrito | 40 | 30 | 11 | 7 | 12 | 34 | 37 | -3 |
| 11 | Boston River | 36 | 30 | 9 | 9 | 12 | 38 | 44 | -6 |
| 12 | Progreso | 36 | 30 | 9 | 9 | 12 | 25 | 33 | -8 |
| 13 | Deportivo Maldonado | 31 | 30 | 8 | 7 | 15 | 24 | 40 | -16 |
| 14 | Sud América | 31 | 30 | 8 | 7 | 15 | 29 | 48 | -19 |
| 15 | Rentistas | 30 | 30 | 8 | 6 | 16 | 30 | 45 | -15 |
| 16 | Villa Española | 14 | 30 | 2 | 8 | 20 | 26 | 60 | -34 |
Campeonato Uruguayo – Descenso 2021
| Pos | Club | Pts | Promedio | PJ | PG | PE | PP | GF | GC | DG |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Nacional | 128 | 1.910 | 67 | 37 | 17 | 13 | 103 | 67 | 36 |
| 2 | Peñarol | 125 | 1.866 | 67 | 34 | 23 | 10 | 103 | 57 | 46 |
| 3 | Montevideo City Torque | 111 | 1.657 | 67 | 32 | 15 | 20 | 116 | 78 | 38 |
| 4 | Liverpool | 107 | 1.597 | 67 | 30 | 17 | 20 | 123 | 89 | 34 |
| 5 | Plaza Colonia | 102 | 1.522 | 67 | 27 | 21 | 19 | 90 | 70 | 20 |
| 6 | Cerro Largo | 98 | 1.463 | 67 | 25 | 23 | 19 | 86 | 72 | 14 |
| 7 | Wanderers | 96 | 1.433 | 67 | 26 | 18 | 23 | 86 | 89 | -3 |
| 8 | River Plate | 91 | 1.358 | 67 | 24 | 19 | 24 | 95 | 91 | 4 |
| 9 | Cerrito | 40 | 1.333 | 30 | 11 | 7 | 12 | 34 | 37 | -3 |
| 10 | Fénix | 89 | 1.328 | 67 | 21 | 26 | 20 | 89 | 87 | 2 |
| 11 | Deportivo Maldonado | 77 | 1.149 | 67 | 19 | 20 | 28 | 71 | 102 | -31 |
| 12 | Rentistas | 77 | 1.149 | 67 | 19 | 20 | 28 | 75 | 93 | -18 |
| 13 | Boston River | 76 | 1.134 | 67 | 19 | 19 | 29 | 81 | 101 | -20 |
| 14 | Progreso | 74 | 1.104 | 67 | 18 | 20 | 29 | 70 | 85 | -15 |
| 15 | Sud América | 31 | 1.033 | 30 | 8 | 7 | 15 | 29 | 48 | -19 |
| 16 | Villa Española | 14 | 0.467 | 30 | 2 | 8 | 20 | 26 | 60 | -34 |
Goleadores – Apertura 2021
| Club | Jugador | Goles | Jugados |
|---|---|---|---|
| - | Gonzalo Bergessio | 12 | 14 |
| Juan Ignacio Ramírez | 11 | 10 |
| Maximiliano Silvera | 11 | 15 |
| Matías Arezo | 11 | 15 |
| Federico Martínez | 9 | 14 |
| Agustín Alvarez Martínez | 8 | 13 |
| Leandro Otormín | 7 | 15 |
| Diogo de Oliveira | 6 | 14 |
| Thiago Borbas | 5 | 15 |
| Gustavo Alles | 5 | 14 |
 | Sebastián Fernández | 5 | 15 |
| Pablo Ceppelini | 5 | 15 |
| Renzo López | 4 | 14 |
| Gustavo Del Prete | 4 | 7 |
| Ruben Bentancourt | 4 | 11 |
| Juan Bautista Cejas | 3 | 12 |
| Lucas Morales | 3 | 10 |
| Maureen Franco | 3 | 12 |
 | Emiliano Villar | 3 | 12 |
| Santiago Paiva | 3 | 11 |
| Luciano Boggio | 3 | 15 |
| Pablo Silva | 3 | 14 |
| Ángel Cayetano | 3 | 14 |
| Luciano Nequecaur | 3 | 8 |
Goleadores - Clausura 2021
| Club | Jugador | Goles | Jugados |
|---|---|---|---|
| - | Salomón Rodríguez | 10 | 14 |
| Maximiliano Silvera | 10 | 15 |
| Lucas Di Yorio | 9 | 13 |
| Sebastián Guerrero | 7 | 15 |
| Hernán Rivero | 6 | 13 |
| Leandro Otormín | 6 | 14 |
| Facundo Labandeira | 6 | 14 |
| Leandro Fernández | 5 | 13 |
| Agustín Alvarez Martínez | 5 | 11 |
| Federico Martínez | 5 | 14 |
| Matías Arezo | 5 | 14 |
| Gastón Colman | 5 | 15 |
| Maureen Franco | 5 | 11 |
| Mauro Méndez | 4 | 13 |
| Lucas Viatri | 4 | 9 |
 | Jorge Ramírez | 4 | 7 |
| Renzo López | 4 | 14 |
| Facundo Torres | 3 | 12 |
 | Nicolás Dibble | 3 | 15 |
| Ignacio Pereira | 3 | 15 |
| Federico Rodríguez | 3 | 13 |
| Pablo Silva | 3 | 9 |
| Pablo Ceppelini | 3 | 14 |
| Rodrigo Amaral | 3 | 15 |
Goleadores – Anual 2021
| Club | Jugador | Goles | Jugados |
|---|---|---|---|
| Maximiliano Silvera | 21 | 30 |
| Matías Arezo | 16 | 29 |
| Gonzalo Bergessio | 15 | 28 |
| Federico Martínez | 14 | 28 |
| Agustín Alvarez Martínez | 13 | 24 |
| Leandro Otormín | 13 | 29 |
| Juan Ignacio Ramírez | 11 | 10 |
| Salomón Rodríguez | 10 | 24 |
| Sebastián Guerrero | 10 | 27 |
| Lucas Di Yorio | 9 | 13 |
| Maureen Franco | 8 | 23 |
| Sebastián Fernández | 8 | 30 |
| Renzo López | 8 | 28 |
| Pablo Ceppelini | 8 | 29 |
| Facundo Labandeira | 8 | 29 |
| Thiago Borbas | 7 | 30 |
| Ruben Bentancourt | 7 | 20 |
| Hernán Rivero | 7 | 26 |
| Leandro Fernández | 7 | 23 |
| Diogo de Oliveira | 6 | 15 |
| Pablo Silva | 6 | 23 |
| Gustavo Alles | 5 | 22 |
| Gastón Colman | 5 | 25 |
| Facundo Torres | 5 | 19 |